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Mahoney Associates, Inc. - Risk Assessment Specialists

Projects:

Portsmouth Naval Shipyard, Kittery, Maine

  • Successfully negotiated USEPA approval for Risk-Based Media Protection Standards for cleanup of air, groundwater, and surface soil for Portsmouth Naval Shipyard, based on human health risks which are specific to the facility.
  • Successfully negotiated USEPA approval for establishing groundwater cleanup levels based on ecological impacts, without the need to consider future residential use of groundwater at a CERCLA site.
  • Successfully demonstrated that the Shipyard was not the source of PCBs found in seafood in the vicinity of the Shipyard, based on a study of PCB concentrations found in seafood throughout the region. This was done as part of a human health risk assessment conducted to assess risks associated with ingestion of lobsters, mussels and flounder caught in the estuary.
  • Successfully negotiated USEPA approval for establishing soil and air cleanup levels based on industrial exposures, without the need to assume future residential exposures, for an active CERCLA facility.

 

Andersen Air Force Base, Guam

  • Successfully negotiated USEPA approval of a technical analysis performed on regional soils background data resulting in no remedial action for soils for several sites.

 

CERCLA Lead Site

  • Successfully negotiated USEPA approval for a soil lead cleanup value based on site-specific information, for a CERCLA site.

 

Expert Witness/Technical Expert

  • Served as an expert witness for USEPA in several litigations involving potential human health risks associated with major releases of PCBs.
  • Served as an expert witness for USEPA in litigations involving the potential human health risks associated with indirect exposures to chemicals released as the result of combustion of hazardous waste.
  • Served as a technical expert for USEPA in conducting technical reviews of human health risk assesssment documents for USEPA Regions 1, 2, 3, 4, and 5 to determine whether documents submitted by regulated parties were in compliance with USEPA and state approved methodologies for conducting risk assessments, and for their technical accuracy.
  • Served as a technical expert for USEPA by performing technical oversight for a Multipathway Human Health Risk Assessment, conducted to evaluate potential health impacts through indirect exposure pathways, of emissions from a hazardous waste incinerator.

 

RCRA/CERCLA

  • Completed dozens of human health risk assessments under RCRA, CERCLA, CAA, and state environmental statutes including those for DOD sites and for corporate clients.
  • Successfully completed human health risk assessments resulting from environmental exposures to lead, arsenic, PAHs, PCBs, dioxins, and many others.

 

Product Safety

  • Completed more than 100 product safety assessments. Designed testing schemes, monitored laboratory studies, evaluated resulting data, documented results and conclusions, and prepared documents for submission to EPA for registration.
  • Established procedures for the evaluation of chemicals for genetic toxicology, qualified laboratories for their expertise in this area, and implemented these procedures for Xerox Corporation.
  • Conducted a critical review of the genetic toxicology data contained in the product dossier of a widely used pesticide for a large pesticide manufacturer. Prepared a technical response to issues raised by EPA and prepared a manuscript for publication of these data.
  • Established procedures for conducting human health risk assessments for product exposures and occupational exposures for Xerox Corporation. Reviewed documents prepared by junior scientists for generation of MSDSs and for compliance with labeling requirements. Participated on corporate committee which developed corporate policies on Environmental Health and Safety.

 

Research

  • Academic research involved studies on the mutagenicity and carcinogenicity of aflatoxin B1 and aflatoxin B1-dichloride, an active derivative of aflatoxin B1 , in human cells in culture. Investigations were carried out on the differential toxicity and mutagenicity of aflatoxin B1 in repair-proficient and repair-deficient human skin fibroblasts in culture. The kinetics of repair were studied in both cell types. The major DNA adducts were isolated and characterized by HPLC and the time course of their loss from the DNA of human cells due to repair processes was examined. A human cell mutation assay using 6-Thioguanine as the selective agent to isolate HGPRT mutants was used. In addition, a human cell-mediated activation system was developed to enable the study of aflatoxin B1 in human cells in culture. 

Mahoney Associates, Inc.
3451 West Queen Lane
Philadelphia, PA 19129
Phone: 215-844-0493

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